Lycium barbarum polysaccharide reduces hyperoxic acute lung injury in mice through Nrf2 pathway
نویسندگان
چکیده
منابع مشابه
Improvement effect of Lycium barbarum polysaccharide on sub-health mice
Objective(s):Sub-health has been described as a chronic condition of unexplained deteriorated physiological function, which falls between health and illness. In the present study, we evaluated the effects of Lycium barbarum polysaccharide (LBP), a polysaccharide fraction purified from Lycium barbarum (L. barbarum) on the sub-health mice. Materials and Methods:The sub-health model mice were buil...
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Lycium barbarum has been used as a traditional Chinese medicine to nourish liver, kidneys and the eyes. However, the underlying mechanisms of its hepatic-protective properties remain uncertain. In this study, we aimed to investigate whether thioredoxin-interacting protein (TXNIP) and NOD-like receptor 3 (NLRP3) inflammasome mediated the attenuation of ethanol-induced hepatic injury by Lycium ba...
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The study is aimed to explore the effects of Lycium barbarum Polysaccharide (LBP), the main active compound of Lycium barbarum, on H2O2-induced oxidative stress in myocardial cells, thereby to investigate the possibility of LBP to be an effective prophylactic agent for cardiac vascular disease (CVD). In the study, rat myocardial cells were randomly divided into control group, H2O2 model group a...
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The incidence of neurodegenerative diseases including Alzheimer's and Parkinson's disease has markedly increased over the past few decades. Oxidative stress is considered to be a common pathophysiological condition resulting in neurotoxicity. Lycium barbarum polysaccharide (LBP) is the major active component of Lycium barbarum L., which exhibit potent antioxidant activity. The current study inv...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2018.12.073